Le bêta-glucane d’orge, contenu dans la fibre de bêta-glucane NutraStat, est une source de fibres alimentaires qui aide à soutenir et à maintenir un système digestif sain. Le bêta-glucane d’orge a montré des effets in vivo sur le microbiote intestinal, entraînant une hausse des acides gras à chaîne courte (AGCC) et des populations de bactéries bénéfiques comme les bactéries lactiques. Les bactéries lactiques offrent des bienfaits potentiels pour la santé, comme le contrôle des infections intestinales et une meilleure digestion du lactose. Sur le plan de la satiété, la recherche a montré que la consommation de bêta-glucane d’orge augmente la viscosité du contenu digestif. Une viscosité plus élevée retarde la vidange gastrique et ralentit le métabolisme et l’absorption des nutriments, plus précisément du glucose, en raison d’une activité enzymatique et d’une absorption par la muqueuse réduites, ce qui procure une sensation de satiété plus rapide.

1. Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236515/
   
2. Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men--a randomized, double-blinded, placebo-controlled trial - PubMed (nih.gov) https://pubmed.ncbi.nlm.nih.gov/18074229/
3. Effects of cereal beta-glucan consumption on body weight, body mass index, waist circumference and total energy intake: A meta-analysis of randomized controlled trials - PubMed (nih.gov) https://pubmed.ncbi.nlm.nih.gov/30935520/
4. Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8624670/
5. Arabinoxylan as well as β-glucan in barley promotes GLP-1 secretion by increasing short-chain fatty acids production - PubMed (nih.gov) https://pubmed.ncbi.nlm.nih.gov/36123993/
6. Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review - PubMed (nih.gov) https://pubmed.ncbi.nlm.nih.gov/38218319/
7. Arena M, Caggianiello G,Fiocco D, Russo P,Torelli M, Spano G, Capozz V. (2014). Barley β-Glucans-Containing Food Enhances Probiotic Performances of Beneficial Bacteria. International Journal of Molecular Sciences. 15(2): 3025–3039. https://www.ncbi.nlm.nih.gov/pubmed/24562330
8. Carlson J, Erickson J, Hess J, Gould T, Slavin J. (2017). Prebiotic Dietary Fiber and Gut Health: Comparing the in Vitro Fermentations of Beta-Glucan, Inulin and Xylooligosaccharide. Nutrients, 9(12): 1361. https://www.ncbi.nlm.nih.gov/pubmed/29244718
9. De Angelis M, Montemurno E, Vannini L, Cosola C, Cavallo N, Gozzi G, Maranzano V, Di Cagno R, Gobbetti M, Gesualdo L. (2015). Effect of whole-grain barley on human fecal microbiota and metabolome. Applied and Environmental Microbiology, 7945-7956. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616929/
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11. Santé Canada. Monographie Bêta-glucane. (2019). https://webprod.hc-sc.gc.ca/nhpid-bdipsn/atReq?atid=beta.glucane&lang=fra
12. Wang Y, Ames N, Li S, Jones P, and Khafipour E. (2014). High molecular weight barley β-glucan supports bacterial populations beneficial for gut health. The faseb Journal, 28:1 supplement. https://doi.org/10.1096/fasebj.28.1_supplement.647.45
13. El Khoury D, Cuda C, Luhovyy B, Anderson G. (2011). Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome. Journal of Nutrition and Metabolism, Vol 2012, 28p. https://www.hindawi.com/journals/jnme/2012/851362/
14. Schroeder N, Gallaher DD, Arndt EA, Marquart L. (2009). Influence of whole grain barley, whole grain wheat, and refined rice-based foods on short-term satiety and energy intake. Appetite. 53(3):363–369. https://www.ncbi.nlm.nih.gov/pubmed/19643157
15. Vitaglione P, Lumaga RB, Montagnese C, Messia MC, Marconi E, Scalfi L. (2010). Satiating effect of a barley beta-glucan-enriched snack. Journal of the American College of Nutrition, 29(2):113–121. https://www.tandfonline.com/doi/abs/10.1080/07315724.2010.10719824
16. Vitaglione P, Lumaga RB, Stanzione A, Scalfi L, Fogliano V. (2009). β-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term. Appetite, 53(3):338–344. https://www.ncbi.nlm.nih.gov/pubmed/19631705

Des études scientifiques ont démontré qu’un apport quotidien d’au moins 3 grammes de bêta-glucane d’orge, l’ingrédient actif de la fibre de bêta-glucane NutraStat, aide à réduire le cholestérol total et le cholestérol à lipoprotéines de basse densité (cholestérol LDL). Ces biomarqueurs sont reconnus comme des facteurs de risque dans le développement des maladies coronariennes. Des études portant sur plus de 1 000 sujets normo- et hypercholestérolémiques ont montré que le bêta-glucane d’orge a réduit les concentrations de cholestérol total et de cholestérol LDL d’environ 0,32 mmol/L et 0,27 mmol/L respectivement, sur une période de 4 à 12 semaines. Les concentrations de cholestérol HDL n’ont pas été touchées.

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3. Behall KM, Scholfield DJ, Hallfrisch J. (2004b). Lipids significantly reduced by diets containing barley in moderately hypercholesterolemic men. The Journal of the American College of Nutrition, 23, 55-62. https://www.ncbi.nlm.nih.gov/pubmed/14963054
4. Bourdon I, Yokoyama W, Davis P, Hudson C, Backus R, Richter D, Knuckles B, Schneeman B. (1999). Postprandial lipid, glucose, insulin, and cholecystokinin responses in men fed barley pasta enriched with β-glucan. American Journal of Clinical Nutrition, 69(1):55–63. https://www.ncbi.nlm.nih.gov/pubmed/9925123
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7. Newman RK, Lewis SE, Newman CW, Boik RJ, Ramage RT. (1989). Hypocholesterolemic effect of barley foods on healthy men. Nutrition reports international, 39, 749-760. https://agris.fao.org/agris-search/search.do?recordID=US8922720
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9. Narain JP, Shukla K, Bijlani RL, Kochhar KP, Karmarkar MG, Bala S, Srivastava LM, Reddy KS. (1992). Metabolic responses to a four-week barley supplement. International Journal of Food Sciences and Nutrition. 43:41-46. https://www.tandfonline.com/doi/abs/10.3109/09637489209027531?journalCode=iijf20
10. Rondanelli M, Opizzi A, Monteferrario F, Klersy C, Cazzola R, Cestaro B. (2011).  Beta-glucan- or rice bran-enriched foods: a comparative crossover clinical trial on lipidic pattern in mildly hypercholesterolemic men. European Journal of Clinical Nutrition. 65(7):864-71. https://www.ncbi.nlm.nih.gov/pubmed/21505506
11. Sima P, Vannucci L, and Vetvicka V. (2018). β-glucans and cholesterol (Review). International Journal of Molecular Medicine, 41(4): 1799–1808. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810204/
12. Shimizu C, Kihara M, Aoe S, Araki S, Ito K, Hayashi K, Watari J, Sakata Y, Ikegami S. (2008). Effect of high β-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men – a randomized, double-blinded, placebo-controlled trial. Plant Foods for Human Nutrition, 63, 21-25. https://www.ncbi.nlm.nih.gov/pubmed/18074229
13. Talati R, Baker WL, Pabilonia MS, White CM and Coleman CI. (2009). The Effects of Barley-Derived Soluble Fiber on Serum Lipids. Annals of Family Medicine, 7, 157-163. https://www.ncbi.nlm.nih.gov/pubmed/19273871

Le bêta-glucane d’orge, l’ingrédient actif de la fibre de bêta-glucane NutraStat, diminue la réponse glycémique après les repas, sans augmenter de façon disproportionnée la réponse insulinique, à des doses d’au moins 4 g par 30 g de glucides disponibles. Des études menées auprès d’hommes atteints de diabète de type 2 ont montré qu’un déjeuner à faible indice glycémique contenant une quantité modeste (3 g) de bêta-glucane pendant 4 semaines permet un bon contrôle de la glycémie. Une alimentation riche en bêta-glucane d’orge peut être bénéfique pour les personnes diabétiques et celles prédisposées aux maladies métaboliques. Parlez à votre médecin avant de modifier votre traitement.

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